The Structural Biology Initiative is a new world-class research center in integrative structural biology at the CUNY Advanced Science Research Center. The SBI combines new faculty, staff and infrastructure to provide research capabilities at the intersection of physics, chemistry and biology – all focused on gaining insights into the mechanisms of nature’s biological machines. Working together with groups across CUNY, at the neighboring NY Structural Biology Center, and throughout the New York community, we are pushing the frontiers of structural biology and its use to answer open questions throughout biomedical science.

ASRC Structural Biology faculty use interdisciplinary approaches to answer pressing biological problems.

Review a list of Structural Biology faculty at the ASRC and elsewhere through the CUNY system.

I. Dikiy, U. R. Edupuganti, R. R. Abzalimov, P. P. Borbat, M. Srivastava, J. H. Freed, K. H. Gardner. (2019) Insights into histidine kinase activation mechanisms from the monomeric blue light sensor. EL346. Proc. Natl. Acad. Sci., DOI: 10.1073/pnas.1813586116.

I. Dikiy, L. Clark, K. H. Gardner, D. M. Rosenbaum. (2019) Isotopic labeling of integral membrane proteins for study by solution NMR relaxation methodsMethods Enzymol., 614: 37-65.

J. Chase, A. Catalano, A. J. Noble, E. T. Eng, P. D. Olinares, K. Molloy, D. Pakotiprapha, M. Samuels, B. Chait, A. des Georges, D. Jeruzalmi. (2018) Mechanisms of opening and closing of the bacterial replicative helicase. eLife, 7, e41140. DOI: 10.7554/eLife.41140