Assistant Professor of Biochemistry, ASRC Structural Biology Initiative
Assistant Professor of Biochemistry, The Graduate Center, CUNY

Shana Elbaum-Garfinkle, Ph.D. is an interdisciplinary scientist, working at the interface of biology, physics and engineering. Her research is at the forefront of a new phase in cell biology where she works to reveal the fundamental principles underlying phase separation of biomolecules into liquid materials. Dr. Elbaum-Garfinkle’s group leverages this new paradigm to identify novel therapeutic targets for treating neurodegenerative diseases including Alzheimer’s disease, ALS, and traumatic brain injury. Employing a diverse expertise in protein biochemistry, material science engineering and C. elegans ​genetics, the Elbaum-Garfinkle group tackles these problems with unprecedented resolution across length scales: spanning the molecular, material, and organismal levels.

Dr. Elbaum-Garfinkle received her Ph.D. from Yale University in Molecular Biophysics and Biochemistry in 2012 after graduating from Hunter College, CUNY and the Thomas Hunter Honors Program with a B.A. in Physics. She then completed a postdoctoral fellowship at Princeton University, where she worked with Clifford Brangwynne. She was awarded the prestigious NIH K99/R00 career award from the National Institute of Neurological Disorders and Stroke to jumpstart her independent research career. Dr. Elbaum-Garfinkle is currently an Assistant Professor in the Structural Biology Initiative at the Advanced Science Research Center, as well as an Assistant Professor of Biochemistry at the Graduate Center, CUNY.

The Elbaum-Garfinkle Lab studies protein liquid phase separation and neurodegenerative aggregation using a combination of single molecule fluorescence, soft matter material science and C. elegans genetics.

Research Interests

Protein and RNA granules, intracellular liquid organelles, and protein assembly and aggregation, neurophysiology and degeneration.