Structural Biology Initiative | Summer 2017

Recent Publications

A. Dashti, D.B. Hail, G. Mashayekhi, P. Schwander, A. des Georges, J. Frank, A. Ourmazd (co-corresponding author) (2018) Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots. bioRxiv: 291922 (pre-print)

S.T. Glantz, E.E. Berlew, Z. Jaber, B.S. Schuster, K. H. Gardner, B.Y. Chow (2018) Directly light-regulated binding of RGS-LOV photoreceptors to anionic membrane phospholipids.  Proc. Natl. Acad. Sci., 115: E7720-E7727

G. Santulli, D. Lewis, A. des Georges, A. R. Marks, J. Frank (2018). Ryanodine receptor structure and function in health and disease. In Membrane Protein Complexes: Structure and Function (pp. 329-352). Springer, Singapore. DOI: 10.1007/978-981-10-7757-9_11

A. Losi, K. H. Gardner, A. Möglich (2018)  Blue-light receptors for optogenetics.  Chem. Rev., in press.  DOI: 10.1021/acs.chemrev.8b00163

A. J. Noble, V. P. Dandey, H. Wei, J. Brasch, J. Chase, P. Acharya, G. Scarpin M. Rapp, E. T. Eg, W. J. Rice, A. Cheng, C. Negro, L. Shapiro, P.D. Kwong, D. Jerulzami, A. des Georges, C. Potter, B. Carragher (2018). Routine single particle CryoEM sample and grid characterization by tomographyeLife7, e34257. DOI: 10.7554/eLife.34257

D.A. Keedy*, Z.B. Hill*, J.T. Biel, E. Kang, T.J. Rettenmaier, J. Brandao-Neto, N.M. Pearce, F. von Delft, J.A. Wells, J.S. Fraser (* contributed equally). (2018) An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering. eLife. DOI: 10.7554/eLife.36307.

L. Calisti, M.C. Trabuco, A. Boffi, C. Testi, L.C. Montemiglio, A. des Georges, et al. (2018) Engineered ferritin for lanthanide binding. PLoS ONE 13(8): e0201859. DOI: 10.1371/journal.pone.0201859

B. B. Minsky, R. R. Abzalimov, C. Niu, Y. Zhao, Z. Kirsch, P. L. Dubin, S. N. Savinov, I. A. Kaltashov (2018) Mass spectrometry reveals a multi-faceted role of glycosaminoglycan chains in factor Xa inactivation by antithrombinBiochemistry. DOI: 10.1021/acs.biochem.8b00199.

B. Johnson (2018) From Raw Data to Protein Backbone: Chemical Shifts Using NMRFx Processing and NMRViewJ Analysis. Methods in Molecular Biology.  DOI: 10.1007/978-1-4939-7386-6_13

L. Clark, I. Dikiy, K. Chapman, K. E. Rödström, J. Aramini, M. LeVine, G. Khelashvili, S. G. F. Rasmussen, K. H. Gardner, D. M. Rosenbaum (2017) Ligand modulation of sidechain dynamics in a wild-type human GPCR. eLife.  DOI: 10.7554/eLife.28505

A. Reade, L. B. Motta-Mena, K. H. Gardner, D. Y. Stanier, O. D. Weiner, S. Woo (2017) TAEL: A zebrafish-optimized optogenetic gene expression system with fine spatial and temporal control. Development. DOI: 10.1242/dev.139238