Structural Biology Initiative | Summer 2017

Recent Publications

Glantz, S.T., Berlew, E.E., Jaber, Z., Schuster, B.S., Gardner, K.H. and Chow, B.Y.  (2018) Directly light-regulated binding of RGS-LOV photoreceptors to anionic membrane phospholipids.  Proc. Natl. Acad. Sci., in press. DOI: 10.1073/pnas.1802832115

Santulli, G., Lewis, D., des Georges, A., Marks, A. R., & Frank, J. (2018). Ryanodine receptor structure and function in health and disease. In Membrane Protein Complexes: Structure and Function (pp. 329-352). Springer, Singapore. DOI: 10.1007/978-981-10-7757-9_11

Losi, A., Gardner, K.H. and Möglich, A. (2018)  Blue-light receptors for optogenetics.  Chem. Rev., in press.  DOI: 10.1021/acs.chemrev.8b00163

Noble, A. J., Dandey, V. P., Wei, H., Brasch, J., Chase, J., Acharya, P., Scarpin G., Rapp, M., Eg, ET., Rice, WJ., Cheng, A., Negro, C., Shapiro, L., Kwong, P.D., Jerulzami, D., des Georges, A., Potter, C., Carragher., B. (2018). Routine single particle CryoEM sample and grid characterization by tomographyeLife7, e34257. DOI: 10.7554/eLife.34257

D.A. Keedy*, Z.B. Hill*, J.T. Biel, E. Kang, T.J. Rettenmaier, J. Brandao-Neto, N.M. Pearce, F. von Delft, J.A. Wells, J.S. Fraser (* contributed equally). (2018) An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering. eLife. DOI: 10.7554/eLife.36307.

Calisti L, Trabuco MC, Boffi A, Testi C, Montemiglio LC, des Georges A, et al. (2018) Engineered ferritin for lanthanide binding. PLoS ONE 13(8): e0201859. DOI: 10.1371/journal.pone.0201859

Minsky B.B., Abzalimov R.R., Niu C., Zhao Y., Kirsch Z., Dubin P.L., Savinov S.N., Kaltashov I.A. (2018) Mass spectrometry reveals a multi-faceted role of glycosaminoglycan chains in factor Xa inactivation by antithrombinBiochemistry. DOI: 10.1021/acs.biochem.8b00199.

Johnson, B. (2018) From Raw Data to Protein Backbone: Chemical Shifts Using NMRFx Processing and NMRViewJ Analysis. Methods in Molecular Biology.  DOI: 10.1007/978-1-4939-7386-6_13

Clark, L., Dikiy, I., Chapman, K., Rödström, K.E., Aramini, J., LeVine, M., Khelashvili, G., Rasmussen, S.G.F., Gardner, K.H. and Rosenbaum, D.M. (2017) Ligand modulation of sidechain dynamics in a wild-type human GPCR. eLife.  DOI: 10.7554/eLife.28505

Reade, A., Motta-Mena, L.B., Gardner, K.H., Stanier, D.Y., Weiner, O.D. and Woo, S. (2017) TAEL: A zebrafish-optimized optogenetic gene expression system with fine spatial and temporal control. Development. DOI: 10.1242/dev.139238