Bruker maXis-II ETD ESI-qTOF

Model

Burker maXis II ETD

Location

Mass Spectrometry

Bruker’s maXis-II ETD ESI-QqTOF instrument is equipped with Dionex Ultimate-3000 LC system. The platform combines latest hardware innovations in TOF technology with unique software packages (including ProteinScape 3.1 for proteomics project management) that deliver sub-ppm mass accuracy and up to 80,000 mass resolution. Key applications include LC-MS/MS (with CID and ETD capabilities) analysis of complex protein/peptide and small molecules mixtures, mass analysis of large non-covalent protein systems.

Application areas:

  • Antibody Characterization – Intact and Subunit Analysis
    Enhanced resolution and mass precision for greater confidence in subunit measurements
  • Complex Protein Mixture
    Superb dynamic range (5 orders of magnitude) for the analysis of complex protein mixture
  • Native Mass Spectrometry (optional)
    The High Mass Option enables analysis of native protein complexes and ADC’s
  • Robust LC-ETD capabilities
    For Top Down Sequence Confirmation on an LC timescale

Manufacturer’s Page

Specifications

  • Bruker’s maXis-II ETD ESI-QqTOF instrument is equipped with Dionex Ultimate-3000 LC system
  • Database system for proteomics project management (ProteinScape 3.1, MASCOT)
  • Sub-ppm mass accuracy (<1ppm)
  • Mass resolution > 80,000 (isotopic resolution even for proteins > 40Kda
  • Applications include LC-MS/MS (with CID and ETD capabilities) analysis of complex protein/peptide and small molecules mixtures , mass analysis of large non-covalent protein systems